![]() ![]() The partial response to hCG stimulation was considered as a hormone level raise for at least 25% and the full response for at least 50% during the test. The morning after 1mg dexamethasone suppression test (1 mg DST), 10.000 IU hCG was administered intramuscularly to all subjects, starting at 0800 h with measurements of cortisol, dehydroepiandrosterone-sulfate, testosterone and aldosterone every 30 minutes for 3 hours. ![]() ![]() All patients underwent standard AI endocrinological evaluation. Methods: Our study group consisted of 39 subjects, 34 patients with AI and 5 age matched healthy controls (63.54 ± 6.91 vs 65.8 ± 3.71 years, P > 0.05). Objective: The objective of our study was to assess the adrenal steroid response to acute, exogenous hCG stimulation in patients with adrenal incidenatalomas (AI) and for the first time, in a healthy control group. Introduction: It is well documented that adrenal tumor tissue is responsive to human chorionic gonadotropin (hCG) as well as to luteinizing hormone (LH) with both hormones sharing a similar physiological role and a mutual receptor. ![]()
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